Phosphatidylserine-mediated adhesion of T-cells to endothelial cells.

نویسندگان

  • J Qu
  • L A Conroy
  • J H Walker
  • F B Wooding
  • J A Lucy
چکیده

Phosphatidylserine was exposed on the surface of human umbilical endothelial cells (ECV304) a few minutes after adding thrombin in vitro, as monitored by prothrombinase assays with and without annexin V. Jurkat T cells adhered to the thrombin-treated cells. The adhesion was inhibited by annexin V, indicating that it was mediated by exposed phosphatidylserine on the endothelial cells.

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عنوان ژورنال:
  • The Biochemical journal

دوره 317 ( Pt 2)  شماره 

صفحات  -

تاریخ انتشار 1996